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EXTRACTABLE NUCLEAR ANTIGEN (ENA complex, anti-RNP antibody, anti-Sm, anti-Smith)

• Uvod Prisutnost • Literatura

Uvod
Ciljni antigen su proteini B, B1 i D koji u kompleksu sa, uridinom bogatom, ribonukleinskom kiselinom čine male jezgrine ribonukleoproteinske čestice (snRNP).

Normalan nalaz: negativan

Prisutnost / Prikazuje ga:
1.         Sistemski lupus eritematodes (SLE) – 25-30% bolesnika
2.         Reumatoid artritis (rheumatoid arthritis) – 1-5% bolesnika
3.         Sjögren -ov sindrom (Sjögren's syndrome)
4.         Mješana bolest vezivnog tkiva (mixed connective tissue disease - MCTD) –
1-5% bolesnika
Literatura:
Barbara A. Bullock, Reet L. Henze, Focus on Pathophysiology
Ravel R.: Clinical Laboratory Medicine, Mosby
Samir P. Desai, MD: Clinical's guide to Laboratory Medicine
Drew Provan: Clinical and Laboratory Investigation (Oxford Handbook)
Topić Elizabeta, Primorac Dragan, Janković Stipan: Medicinskobiokemijska dijagnostika u praksi
 

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Home Laboratorij EXTRACTABLE NUCLEAR ANTIGEN (ENA complex, anti-RNP antibody, anti-Sm, anti-Smith)